National Cancer Institute
Twitter facebook linked in Email

Coordinating Center for the Cancer Systems Biology Consortium and the Physical Sciences-Oncology Network (U24)

Seattle, WA

Overview | Investigators | Projects


Coordinating Center for the Cancer Systems Biology Consortium and the Physical Sciences-Oncology Network

Center Name

Sage Bionetworks

Center Website

List of Collaborating Institutions

List any and all institutions your center collaborates with.

Center Summary

Sage Bionetworks is a nonprofit biomedical research organization, founded in 2009, with a vision to promote innovations in personalized medicine by enabling a community-based approach to scientific inquiries and discoveries. Sage Bionetworks strives to activate patients and to incentivize scientists, funders and researchers to work in fundamentally new ways in order to shape research, accelerate access to knowledge and transform human health. Sage is located on the campus of the Fred Hutchinson Cancer Research Center in Seattle, Washington and is supported through a portfolio of philanthropic donations, competitive research grants, and commercial partnerships.

Back To Top



Justin Guinney, Ph.D.

Justin Guinney is Director of Computational Oncology at Sage Bionetworks, and oversees Sage’s cancer research programs. Dr Guinney earned his PhD in computational biology at Duke University in 2009, and joined Sage that same year as a research scientist. Dr Guinney’s lab specializes in genomic data analysis for prognostic and predictive modeling of cancer outcomes and response to therapy. In support of Sage’s underlying mission to promote open systems and incentives for data sharing and collaboration, Dr Guinney has leadership roles in several “open science” initiatives including the Colorectal Cancer Subtyping Consortium, the GENIE consortium, and the DREAM Challenges consortium.

Back To Top



As the U24 coordinating center for the CSBC and PS-ON, Sage Bionetworks will facilitate cross-project collaboration and analysis through three primary hubs, described below.

  • Resource Hub: The resource hub will serve as a clearinghouse for all data generated by the CSBC and PS-ON-funded projects. Sage has developed a software platform, Synapse, that provides a platform by which scientists can collaboratively work on biomedical research projects. This platform will house all data and methods and serve as a way to make the data publicly available.
  • Outreach Hub: The outreach hub works to connect the CSBC and PS-ON to the greater scientific community through the website at, hosted talks and a quarterly newsletter.
  • Collaboration and Pilot Project Hub: The third hub is focused on actively working to get the independent centers and projects funded through the CSBC and PS-ON initiatives to work together though pilot projects that combine the expertise of two or more centers. Furthermore, this hub will capitalize on the relationship between Sage Bionetworks and the DREAM organization to introduce large cancer-specific datasets to the community by hosting competitions to better understand the data.

Back To Top