National Cancer Institute
U.S. National Institute of Health www.cancer.gov National Cancer Institute
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FEATURED CENTER

 
The Scripps Research Institute

The Scripps Research Institute
The Scripps Research Institute Physical Sciences-Oncology Center (TSRI PS-OC) incorporates a trans-disciplinary effort from celebrated physicists and oncologists to pursue the mechanisms that regulate the survival of circulating tumor cells. These investigators will probe the biophysical factors implicated in the endurance of individual circulating tumor cells while in the blood stream and in their progression to metastatic disease. Fluid phase biopsies from epithelial cancers such as lung cancer will be employed to assess and model the physical attributes of these tumor cells over the course of the disease across various body compartments. In addition, this center will utilize highly sophisticated, quantitative physical science techniques to analyze patient samples in terms of cell size, mechanical properties and ultrastructural complexity. This unprecedented approach should deliver a rich database for further longitudinal statistical and mathematical analysis and yield much needed insight into the behavior, survival and destination of circulating tumor cells.
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CENTERS

 
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Physical Science-Oncology Centers

The National Cancer Institute (NCI) has awarded cooperative agreements to 12 leading institutions to build a collaborative network of Physical Science-Oncology Centers (PS-OCs).

 

PHYSICAL SCIENCES-ONCOLOGY CENTERS

 
Arizona State University Arizona State University
Physical Sciences-Oncology Center
Arizona State University, Tempe, AZ

Principal Investigator: Paul Davies, Ph.D.
Scientific Investigator: William M. Grady, M.D.
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Dana-Farber Cancer Institute Dana-Farber Cancer Institute
Physical Sciences-Oncology Center
Dana-Farber Cancer Institute, Boston, MA

Principal Investigator: Franziska Michor, Ph.D.
Scientific Investigator: Eric C. Holland, M.D., Ph.D.
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Johns Hopkins University Johns Hopkins University
Physical Sciences-Oncology Center
Johns Hopkins University, Baltimore, MD

Principal Investigator: Denis Wirtz, Ph.D.
Scientific Investigator: Gregg L. Semenza, M.D., Ph.D.
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The Methodist Hospital Research Institute The Methodist Hospital Research Institute
Physical Sciences-Oncology Center
The Methodist Hospital Research Institute, Houston, TX

Principal Investigator: Mauro Ferrari, Ph.D.
Scientific Investigator: Steven A. Curley, M.D.
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Princeton University Princeton University
Physical Sciences-Oncology Center
Princeton University, Princeton, NJ

Principal Investigator: Robert H. Austin, Ph.D.
Scientific Investigator: Thea D. Tlsty, Ph.D.
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Stanford University Stanford University
Physical Sciences-Oncology Center
Stanford University, Palo Alto, CA

Principal Investigator: Jan Liphardt, Ph.D.
Scientific Investigator: Valerie M. Weaver, Ph.D.
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Cornell University Cornell University
Physical Sciences-Oncology Center
Cornell University, Ithaca, NY

Principal Investigator: Michael L. Shuler, Ph.D.
Scientific Investigator: Barbara L. Hempstead, M.D., Ph.D.
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H. Lee Moffitt Cancer Center & Research Institute H. Lee Moffitt Cancer Center & Research Institute
Physical Sciences-Oncology Center
H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL

Principal Investigator: Robert A. Gatenby, M.D.
Scientific Investigator: Robert J. Gillies, Ph.D.
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Massachusetts Institute of Technology Massachusetts Institute of Technology
Physical Sciences-Oncology Center
Massachusetts Institute of Technology, Cambridge, MA

Principal Investigator: Scott Manalis, Ph.D.
Scientific Investigator: Tyler Jacks, Ph.D.
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Northwestern University Northwestern University
Physical Sciences-Oncology Center
Northwestern University, Chicago, IL

Principal Investigator: Thomas V. O'Halloran, Ph.D.
Scientific Investigator: Jonathan D. Licht, M.D.
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The Scripps Research Institute The Scripps Research Institute
Physical Sciences-Oncology Center
The Scripps Research Institute, La Jolla, CA

Principal Investigator: Peter Kuhn, Ph.D.
Scientific Investigator: Kelly J. Bethel, M.D.
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University Of Southern California University Of Southern California
Physical Sciences-Oncology Center
University of Southern California, Los Angeles, CA

Principal Investigator: W. Daniel Hillis, Ph.D.
Scientific Investigator: David B. Agus, M.D.
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